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The first 1 mg engages more of the GIP receptor than the next 11 mg combined. GLP-1 appetite suppression continues to rise, but the added benefit narrows in the higher bands while side effects keep increasing

Human clinical studies conducted in the past also show that Epitalon treatment significantly reduced the risk of developing age-related neurodegenerative diseases, such as Alzheimers, dementia, heart disease, etc

10.1016/j.regpep.2009.11.005 39 GojkovicS.KrezicI.VrdoljakB.MalekinusicD.BarisicI.PetrovicA.et al (2020)

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Weight change typically reflects an individual's energy balance, daily movement, sleep patterns, appetite, stress levels, and adherence to a diet over time