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JAMA 309.12 (2013): 1241-1250
R.ApplebaumS
The strongest human clinical evidence is for topical use, including the Leyden 2002 photoaging trial and a 2023 NEEL gel topical study reporting an average 28% increase in skin collagen density at 3 months
It stimulates blood vessel and nerve growth to reduce wrinkles and improve skin firmness, elasticity and clarity, GHK-Cu has shown efficacy in hair growth as well increasing both hair length and thickness, meanwhile enlarging the hair follicle size
Diabetes Nutr Metab 17:95102 Chanson A, Rock E, Martin JF, Liotard A, Brachet P (2007) Preferential response of glutathione-related enzymes to folate-dependent changes in the redox state of rat liver
(vi) comorbid diagnosis: Fragile X syndrome, tuberous sclerosis, phenylketonuria or fetal alcohol syndrome or (vii) acute illness
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