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This means it mimics the GLP-1 hormone, which is released in your digestive tract when you eat
In April 2026, the Medicines and Healthcare products Regulatory Agency (MHRA) approved an update to the product information for Wegovy (semaglutide) FlexTouch pens
In clinical trials, tirzepatide (SURMOUNT-1) showed up to 22% average weight loss, while semaglutide (STEP-1) resulted in around 15%though these trials were not head-to-head comparisons
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If you have a history of pancreatitis, gallstones, thyroid cancer, or a very low BMI, ask your doctor whether these medicines are safe for you before starting
This treatment option is especially beneficial for individuals with prediabetes, insulin resistance, or metabolic syndrome
doi: 10.1016/S0140-6736(18)30726-8 83 EngJKleinmanWASinghLSinghGRaufmanJP
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