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In some parts of China (e.g., Keshan), the intake was only 314 g/day (56, 57), and the endemic Se deficiency appeared in the form of chronic osteochondropathy (KashinBeck disease) and chronic cardiomyopathy (Keshan disease), which are now preventable through Se supplementation (71, 72)
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Consequently, it has implications for every system, from the heart to the brain
Remarkably, the survival benefits of GLP-1RAs, as observed in CVOTs, typically manifest over a more extended period than what our Kaplan Meier curves suggest 15,33
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