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Interestingly, the specific ablation of GPR119 only in -cells does not affect glucose tolerance nor insulin secretion

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Management of lower back pain in patients taking semaglutide should follow evidence-based guidelines for acute and chronic lower back pain, with consideration of the patient's overall metabolic health and treatment goals

Longer-term clinical studies and real-world evidence will be essential to better characterize the safety profile of cagrilintide-semaglutide, particularly regarding uncommon adverse events, treatment persistence, and its effects on body composition and bone health