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Centers for Disease Control and Prevention (CDC) data show that over 100 million US adults are obese, PwC noted, while an analysis published in JAMA Cardiology in November determined that 137 million Americans may be eligible for the GLP-1 drug semaglutide (prescribed as Wegovy for weight loss and Ozempic for type 2 diabetes)
GLP-1 medications can cause GLP-1 fatigue
doi: 10.1047/jbc.M412521200 73 European Medicines Agency (2020)
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Studies looking at people with central adiposity show: An anterior shift of the whole-body center of mass, which challenges balance and increases the work of spinal and hip musculature
Only 84% as many patients are active on insulins at month 12 as compared to month 0 of GLP1 therapy
Plasma SCFAs Lactate, acetate, 2-hydroxybutyrate, and isovalerate were detected in plasma samples of most subjects but we failed to detect any effect of inulin, MDX, or surgery on plasma SCFAs
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