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Long-term safety beyond 12 weeks has not been formally studied in large populations
In metformins own drug trials, about 7 in 100 patients who started with a normal B12 level dropped to a low one over roughly 29 weeks
Science advances
Published oral AOD-9604 trials lasted 12 or 24 weeks
The dual growth hormone releasing peptide mechanism is one reason clinicians favor this combination over older peptide protocols
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