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Arsenic occurs naturally in the soil in some areas of the world and can leach into well water

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Mitigation strategies include strict adherence to the titration schedule, eating smaller and more frequent meals, avoiding high-fat and greasy foods, staying well hydrated, and eating slowly

Am J Cardiol 1997

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Patients must also consider the financial implications, as off-label use may not be NHS-funded, potentially incurring substantial private costs