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However, there is no evidence that maternal homocysteine is a causative factor in neonatal brain development but measurement of maternal homocysteine concentration may provide an insight into the efficiency of the methionine cycle and provision of methyl groups (one carbon metabolism) during pregnancy

doi:10.1016/s0033-0620(97)80037-0 Fisher JS, Gao J, Han DH, Holloszy JO, Nolte LA

This process is critical for regulating energy levels, particularly during fasting or prolonged physical exercise [4, 39, 40]

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Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice