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Threlfell, Sarah, et al

For example, Lactiplantibacillus plantarum reduces the DNA-binding capacity of NF-B, thereby limiting the transcription of pro-inflammatory genes (258), whereas Lactobacillus brevis inhibits the phosphorylation of upstream kinases such as IRAK1 and AKT (259)

445 This implies that ERK can indirectly activate Cdc42 and Rac at the leading edge, promoting actin polymerization

Experimental findings also indicate that thymosin-related peptides can influence macrophage polarization and functional activity, while GHK-Culinked pathways affect inflammatory signaling networks associated with leukocyte mobilization and tissue remodeling (31,33,35)

Lightens skin by reducing total melanin production and converting darker eumelanin into lighter pheomelanin