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L., Farzi, A

Succinate is an inflammatory signal that induces IL-1 through HIF-1

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The diagnosis of Hashimotos thyroiditis may be made when you have symptoms of hypothyroidism, and a blood test shows an underactive thyroid gland [an elevated Thyroid Stimulating Hormone (TSH) level with or without a low thyroid hormone (free T4 or total T4) level]