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First, the route of administration

Human safety and efficacy remain completely unestablished

Takata Y, Shrubsole MJ, Li H, et al

The clinical decision on protocol length and maintenance frequency is made at the APRN evaluation based on the individual patients response and goals

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NAD binding site of diphtheria toxin: identification of a residue within the [PMID: 6145155] Laboratory literature summary: NAD binding site of diphtheria toxin: identification of a residue within the nicotinamide subsite by photochemical modification with NAD