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Wegovy is a medication that significantly impacts the gastrointestinal tract and directly communicates with the appetite centre in the brain, the hypothalamus
Beginners typically start at 300mcg to assess tolerance and response
In populations of adults with overweight or obesity, use of tirzepatide was associated with significantly greater weight loss than semaglutide [26] [27], suggesting that the superior efficacy observed in controlled trials translates to clinical practice
Consider: Skin sensitivity and realistic expectations
Interestingly, physical function and QoL were not improved at the end of 8-weeks in any study arm
Semaglutide is not recommended during pregnancy because of the potential risks of birth defects, low birth weight, and miscarriage
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