Microdosing GLP-1s is a popular topic, especially on social media
The disconnect between preclinical efficacy and human clinical outcomes remains unexplained and represents a significant limitation for potential therapeutic applications
In terms of overall business developments, the single biggest update from Lilly's latest report is that the FDA approved Foundayo as the first oral GLP-1 agonist for obesity that can be taken at any time of day and without any restrictions related to food or water
Sperm counts have dropped worldwide
These findings are consistent with a large body of preclinical data supporting the critical role of serotonin in modulating gut development and function, although further research is necessary to determine the long-term effects of maternal depression and SSRI exposure on the development of common gastrointestinal disorders
Kber F, Heimann Y, Lehmann T, Schleuner E, Proquitt H, Groten T