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Calcidiol can also be hydroxylated at the 24 position by a specific vitamin D 3 -24-hydroxylase (encoded by the CYP24A1 gene) in the kidneys, intestine, placenta, and cartilage which are all tissues that express the VDR
Recognise the importance of maintaining glutathione levels as part of their dietary intake
At moderate oxidative stress this effect small
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Implications for treatment selection As combination products become more common, the distinction between insulin and GLP-1 therapy becomes more important, not less
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