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ACSL4 catalyzes the esterification of free AA and AdA with coenzyme A (CoA) to form PUFA-CoA derivatives (AA-CoA or AdA-CoA) (Liu et al., 2022a)

Integrative oncology studies and protocols are a key translational interface in which TS are being evaluated, with the aim to comprehensively evaluate their therapeutic potential, safety, pharmacokinetics and clinical efficacy, attempting to connect preclinical mechanistic findings with evidence-based clinical practice

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Int J Mol Sci (2021) 22:8532

Melanotan II is C-terminally amidated (-NH) and acts broadly across the melanocortin receptor family