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Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia
This is often when more noticeable changes may begin to appear, including: Firmer-looking skin More even-looking texture Continued improvement in the appearance of fine lines Ongoing support for skin renewal A clinical study summarized in a review reported visible skin improvements over about 12 weeks , including better skin density, thickness, and wrinkle appearance
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