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Other Medications Certain antidepressants or psychiatric medications : While not a direct contraindication, medications that affect appetite or metabolism, such as SSRIs or antipsychotics , may influence how well Semaglutide works or contribute to side effects like nausea
The data provides population averages, but your experience will be individual
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Following administration of a combined oral contraceptive (0.035 mg ethinyl estradiol and 0.25 mg norgestimate) in the presence of a single dose of tirzepatide 5 mg, mean Cmax of ethinyl estradiol, norgestimate, and norelgestromin was reduced by 59%,66%, and 55%, while mean AUC was reduced by 20%, 21%, and 23%, respectively
Blood pressure reductions averaged 6.8 mmHg systolic across the trial population
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