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doi:10.1016/S2213-8587(17)30085-2 Newsome, P
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On raw weight-loss numbers, retatrutide reached a numerically larger mean reduction (about 24% at 48 weeks in phase 2) than tirzepatide (about 22.5% at 72 weeks in phase 3), and its sponsor-reported phase 3 topline figures are higher still
Cytokine-stimulated immune cells can also promote HPA axis activation and GC signaling by upregulating the production of corticotrophin-releasing hormone (CRH) in the hypothalamus (181)
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