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58 GLP-1RAs potentially may reduce the risk of AF onset and progression through direct and indirect effects on atrial remodelling, including a reduction in systemic inflammation, improvement of cardiomyocyte metabolism, autonomic nervous system modulation, regulation of intracellular Ca 2+ levels and prevention and possibly reversion of atrial fibrosis
ROS is considered the crucial component of the activation of the ubiquitin-proteasome system
Several next-generation programmes are exploring therapies designed to preserve lean muscle mass during weight loss, an increasingly important clinical objective as obesity therapies become more widely used
Meta-analysis of short sleep duration and obesity in children and adults
BPC-157 es un fragmento pentadecapeptdico derivado del sistema gstrico que ha sido ampliamente investigado en estudios preclnicos por su papel en la proteccin tisular, sealizacin angiognica, integridad microvascular y modulacin de vas inflamatorias
2,3 GLP-1RAs influence the hypothalamic-pituitary-ovarian axis, enhancing gonadotropin secretion and improving ovarian function
