The ratio of Firmicutes to Bacteroidetes is a commonly-studied change with an increase often linked to HFD consumption/obesity in mice 43,44 and humans 45,46 (for review, see John and Mullin, 2016 47 )
Consistent with the higher fold-change in lipid ROS levels seen in MUTU I, erastin also caused higher levels of cell death in MUTU I treated for 24 hours, which could be rescued by Fer-1, indicative of ferroptosis (Fig 4B, S5B)
Food noise and the gut brain connection When we talk about food noise we mean the persistent internal chatter that pushes us toward snacks, sweets and overeating
For cardiomyopathy, GLP-1RAs improve mitochondrial function via regulating autophagy and inflammatory signaling, as well as not only mediate the inhibition of myocardial apoptosis, but also improve cardiac energy metabolism
Good stuff, no doubt
new collagen cannot replace losses and results in disease (scurvy)