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Subcutaneous injection bypasses all of these barriers except plasma half-life, which for unmodified small peptides is generally very short (minutes to low hours, based on class-level pharmacokinetic data for similar unmodified peptides)
vulgaris, which inhibits lipid absorption and transport in the gastrointestinal tract, thus lowering plasma lipid levels and promoting weight loss [47]
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Some patients start with weekly injections, then transition to monthly maintenance once levels stabilize
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