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Preclinical safety data In mouse studies, 5-amino-1mq was well-tolerated even at doses several times higher than those producing metabolic effects
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The peptide appears to act through direct interaction with adipocytes (fat cells), potentially involving activation of hormone-sensitive lipase (HSL) and modulation of -adrenergic receptor signaling pathways
This interaction also hints at DSIP's potential role in managing stress tolerance, given the significant influence of alpha 1-adrenergic signaling in stress-related processes
For chronic overdoses, NAC is considered in patients who have exceeded safe daily limits, typically more than 4 g/day in adults or 120 mg/kg/day in children
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