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As fat melts away, so do the soft curves of the face, sometimes revealing sagging cheeks, deeper folds, and a more aged appearance

Currently, there is no robust evidence to suggest that GLP-1 receptor agonists directly impair thermoregulation through pharmacological action on temperature control centres in the hypothalamus

Methylmalonyl-CoA mutase is one of only two vitamin B12 requiring enzymes in humans (the other is methionine synthase)

Gastrointestinal distress may be amplified when combining both approaches, potentially leading to dehydration, electrolyte imbalances, and poor nutritional intake

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