are there any long term side effects of semaglutide I am not surprised by a new report showing that two-thirds (Ozempic) users quit taking the medication within a year. These drugs not a long-term solution, and the Long-Term Side Effects of Wegovy:

Shikora et al

Future research should examine the potential role of GLP-1RAs in the treatment and prognosis of psychiatric and neurodevelopmental conditions

no androgenic benefit

DOI: 10.1038/s41586-024-07685-6 This work was supported by the National Institutes of Health (R00DK119574 and DP2AT011965), the American Heart Association, New York Stem Cell Foundation, Klingenstein Fund and Simons Foundation, Pew Charitable Trusts, National Science Foundation (Grant2236662), the Penn Institute for Diabetes, Obesity, and Metabolism, and the Monell Chemical Senses Center

one histidine is bound between the two metals

The regulatory pathway for OTC APIs is less intensive than for prescription products but is not exempt from GMP requirements