This investigation was based on adverse event reports submitted to the FDA Adverse Event Reporting System (FAERS)
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declares funding to conduct clinical trials from AstraZeneca, Bayer, Boehringer Ingelheim and Novo Nordisk (all to the INCLIVA Research Institute)
These adaptations persist for years, possibly permanently, after weight loss
Tirzepatide is a novel glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist licensed in the UK for the treatment of type 2 diabetes mellitus and, more recently, for chronic weight management in adults with obesity or overweight with weight-related comorbidities, as per the MHRA Summary of Product Characteristics
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