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263 Similarly, in HCC, the oncofetal protein CLDN6 competes with TJP2 for YAP1 binding via its PDZ domain, displacing YAP1 from tight junctions and facilitating its nuclear localization
At 6h/day exposure, BE PVM/MA triggered upregulation of a higher number of biomarkers, such as IL-6 and IL-8 (Supplementary Figure S1)
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S-Acetyl L-Glutathione achieves this through elegant biochemistry: the acetyl group acts as a protective shield during absorption, then gets cleaved off by cellular enzymes to release active glutathione directly into tissues like the liver, lungs, and brain
