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doi:10.3390/ani11113161
Patient-derived hiPSC-neural models (paired with isogenic or familial controls) have already revealed important mechanistic details, and in some cases have elucidated therapeutic vulnerabilities, for many genetic disorders (Paca et al., 2011
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This dual approach is particularly relevant for MASH, where hepatic steatosis is directly targeted by glucagon-mediated fat oxidation
Although these measures partially improve testicular thermoregulation, their efficacy is limited when irreversible testicular damage occurs
Tirzepatide tends to produce higher weight loss numbers because it targets two hormone pathways instead of one
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