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A 2025 systematic review in Orthopaedic Sports Medicine analyzed 36 studies on BPC-157 and found that the peptide improved functional, structural, and biomechanical outcomes in muscle, tendon, ligament, and bone injury models

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In recent years, certain peptides have gained attention as potential treatments for erectile dysfunction (ED), though their use remains largely experimental and outside mainstream clinical practice in the UK

Instead of overcoming the metabolic adaptation, higher doses frequently exacerbate side effects like nausea, fatigue, and gastrointestinal distress

In other cases, the cause is unknown (idiopathic), likely from a mix of genes, metabolism, and immune issues