[4] The most frequently reported adverse effects include transient gastrointestinal discomfort-nausea, vomiting, abdominal cramps, or diarrhea-particularly when large doses are delivered rapidly
Introduction Trisomy 21 (T21), which causes Down syndrome (DS) (OMIM 190685) ( One of the clinical comorbidities of subjects with DS is the alteration of the immune system
However, other randomized controlled trials have not found any benefit of citicoline treatment in the management of acute ischemic stroke (98, 99), including a recent trial evaluating its effects when provided immediately following endovascular thrombectomy (i.e., recanalization therapy) and continued for 42 days (100)
Some studies have identified metabolic deficiencies in autistic children [14], and it has recently been shown that there is a characteristic metabolic profile in many autistic children involving disturbances in methionine and glutathione metabolism [14, 15]
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