There is also the risk of long-term bone density loss, possibly resulting in fractured bones
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2.2 Recommended Dosage Recommended Initiation Dosage Initiate OZEMPIC with a dosage of 0.25 mg injected subcutaneously once weekly for 4 weeks
The Harmony Outcomes post-hoc analysis also showed a similar trend with respect to MACE and HHF, although kidney outcomes were not examined (Table 3) [48]
Higher doses of any GLP-1 receptor agonistwhether semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), or tirzepatidecorrelate with increased gastrointestinal adverse events