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Once exposed to room temperature for extended periods, the vial should not be returned to refrigerated storage and used beyond the 21-day window
Another example: individuals with chronic alcoholism often need prolonged thiamine/B-complex support
Ivell, R., Richter, D., & Balvers, M
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C., Chaturvedi, M
Oral preconditioning of rats with 50 or 100 mg/kg/day for 7 days significantly reduced markers of liver damage (ALT, AST, and lipid peroxidation) following experimental acetaminophen overdose (Girish 2009)
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