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The peptide differs from natural GHRH as it has been modified for optimal stability by manipulating the N terminus of the compound

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doi: 10.1200/jco.2017.72.7735

CopperTripeptide-1is naturally occurring in the body, it is composed of the amino acidsGlycyl-histidyl-lysine, which spontaneously bind to copper, also known asGHK-Cu