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While semaglutide and tirzepatide have helped thousands of patients, some individuals still experience weight plateaus

These patients may differ in baseline characteristics, behavioral factors, or comorbidity burden compared with those achieving optimal surgical outcomes, introducing potential selection bias inherent to retrospective designs

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Moreover, in individuals with type 2 diabetes, metformin may provide cardiovascular protection that is not solely attributed to its glucose-lowering effects, as it also has antihypertensive effects [23]

11 An increased concentration of TRX-1 had a positive effect on the activity of other antioxidants such as manganese superoxide dismutase and GSH peroxidase

That said, there is nothing wrong with asking whether peptide therapy could play a supporting role in your overall plan