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The copper ion facilitates these reactions when energized by light photons
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Yes, refrigerating an opened vial at 2 to 8C is acceptable and will not damage it
However, for patients with severe symptomatic hyponatremia who are particularly prone to overcorrectionespecially those at high risk for ODS where consistent monitoring of laboratory values and urine output is challengingearly use of DDAVP can be considered a proactive and viable strategy
To date, the parenteral, generally intramuscular, lifelong administration of hydroxycobalamin (OHCbl) is the mainstay of therapy in these disorders
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