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The fixed-effect model revealed a significant reduction in GSH levels in individuals with malaria compared with uninfected controls ( P = 0.01, Hedges g: 0.12, 95% CI 0.21 to 0.03), as confirmed by the meta-analysis of 17 studies ( I 2 : 99.12%, Supplementary Fig

The apolipoprotein E (APOE) genotype was determined using imputed genotypes of SNPs rs429358 (APOE 4) and rs7412 (APOE 2) 26,27

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