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(5) The apparent closure rate was three times faster than standard care

Subsequent work by Heffernan and coworkers (2001) confirmed the peptides effects in obese mouse models, with chronic administration associated with reduced body weight gain and decreased adiposity without concurrent changes in food intake

There may be a link between A accumulation and NMDA receptor over activation in that oxidative stress, plus the elevated intracellular calcium generated due to A accumulation, appear to enhance glutamate mediated neurotoxicity via increased NMDA receptor activation (42)

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