J Clin Pharmacol (2015) 55:1528
Long-term clinical trials will be needed to address this question
As with fetal glucocorticoids, postnatal glucocorticoids or stress can alter synaptic pruning and can also lead to reduced GR expression in brain regions important for glucocorticoid negative feedback, the hypothalamus and hippocampus (Liu et al., 1997)
The mechanism is specific: BPC-157 promotes the repair of tight junctions, the protein structures that hold intestinal epithelial cells together and prevent undigested particles from passing through the gut wall into systemic circulation
The agency does the final paperwork either way
Drenning JA, Lira VA, Soltow QA, Canon CN, Valera LM, Brown DL, Criswell DS