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It binds to the 50S ribosomal subunit, preventing the formation of the functional 70S initiation complex required for translation (Leach et al., 2011
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Geneva: ICH, 2000
Do najczstszych dziaa niepodanych naleay: nudnoci, biegunka, wymioty, zaparcia, ble brzucha, zmniejszenie apetytu
Some states impose specific protocols for weight-loss prescribing (Florida and New Jersey have detailed regulations), but these apply equally to all physicians
Leading to wildly inaccurate dosing that compromises study outcomes and increases the risk of adverse effects like nausea, facial flushing, and spontaneous erections in male subjects
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