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However, the results may be influenced by external factors including inflammation, growth factors and organ dysfunctions ( via organ biopsies or imaging methods as biomagnetic susceptometry or magnetic resonance imaging (MRI) although these methods are rarely applied due to their invasiveness, costs or insufficient validation ( Using this variety of methods, over the years several characteristics of an altered iron metabolism in MDS and AML patients have been found together indicating a state of iron overload in these diseases ( Figure 2B )

Targeting GST therefore provides a mechanistically relevant way to evaluate whether microbes-derived metabolites can interfere with this detoxification system and potentially sensitise bacteria to existing antibiotics

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Potentially deleterious reactive oxygen species (ie, superoxides, peroxides, and hydroxyl radicals) are produced during the oxidation of fuels (oxidative phosphorylation) in mitochondria as byproducts of the utilization of molecular oxygen in the electron transport chain

It is researched for soft tissue injuries including tendon and ligament damage relevant to the knee

Curr Med Chem 2006