Drug solutions, typically 5 mg/ml in HPLC-grade water (except for Dihexa, prepared in DMSO), were added to rat serum, and the mixture was incubated at 37C
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AOD-9604 remains an unapproved investigational compound in the United States)
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The reasons for variable expression of CHAC1 in different cancers are still unclear, but it appears to be critically dependent on TP53 status
Body composition changes (fat loss, improved recovery) become noticeable at weeks 4 to 8