The reasoning behind this restriction ties back to concerns about cardiovascular effects and the potential for tolerance, where the drug becomes less effective over time as the body adapts to elevated norepinephrine levels
Given this complex landscape, it becomes clear why just reaching for a B12 shot without understanding the root cause might not be the magic bullet you hope for
The growth-hormone axis is the chain researchers study here: the brain sends a hormone called GHRH to the pituitary gland, the gland releases growth hormone, and growth hormone prompts the liver to make IGF-1
S.ChandranR.de Souza AraujoA
Brockmeyer DL, Sivakumar W, Mazur MD, Sayama CM, Goldstein HE, Lew SM, Hankinson TC, Anderson RCE, Jea A, Aldana PR, Proctor M, Hedequist D, Riva-Cambrin JK
Oxidative stress may also down-regulate other essential enzyme systems associated with the methionine cycle, including methionine synthase, betaine-homocysteine methyltransferase and methionine adenosyltransferase, leading to further monoamine neurotransmitter disruption and weakening of antioxidant enzyme activities (Guildford)