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The approach addresses biological factorsmetabolism, hormones, appetite regulationthat lifestyle changes alone may not fully reach

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7 In fact, xCT is considered to be the main transporter of cystine in cancer (Table 1) 25,26,27 and its expression is controlled by nuclear factor erythroid 2-related factor 2 (NRF2), a master regulator of the cellular redox state, 28 highlighting the importance of xCT in an oxidative stress-resistant cancer cell phenotype

Association of PCSK1 Rs6234 with Obesity and Related Traits in a Chinese Han Population. PloS One, vol