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Theres no current evidence of addiction, but mental reliance can develop if misused
JAMA 325 , 14031413 (2021)
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Other organisms such as Helicobacter pylori (responsible for ulcers and cases of severe heartburn) or giardia (a parasite) can also eat away at the intestinal lining
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When released extracellularly, HMGB1 acts as an alarmin that modulates inflammation and immune responses
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