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Published online February 2, 2024 DOI: 26,358 View 743 Download 47 Web of Science 51 Crossref Abstract PDFPubReader ePub It has been generally accepted that insulin resistance (IR) and reduced insulin secretory capacity are the basic pathogenesis of type 2 diabetes mellitus (T2DM)

Subsequently, alkyl-DHAP is reduced by alkyl-DHAP reductase (ADHAPR/DHRS7B) to 1-O-alkyl-2-hydroxy-glycerol-3-phosphate (GPA)

These effects collectively contribute to improved survival outcomes and cognitive function in cecal ligation and puncture (CLP) mouse models

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However, given the positive CV outcomes, a slight increased heart rate doesnt seem to translate into adverse outcomes