Although patients receiving exenatide IR and experiencing longer durations of nausea and vomiting tended to lose more weight, those in the trial group who did not experience the gastrointestinal symptoms (70%) generally lost weight as well (166, 224)
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In clinical trials, tesamorelin produces selective effects: Visceral adipose tissue decreases Lean mass is preserved or modestly increased Hepatic fat fraction drops The visceral fat reduction creates a feedback loop
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