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J Biol Chem 263(18):86218624 Reimann F, Gribble FM (2002) Glucose-sensing in glucagon-like peptide-1-secreting cells
Emission was recorded with an Orca-ER CCD camera (Hamamatsu, UK) whilst cells were continuously perfused at ~1 ml min 1
Benefits of Peptide Therapy Over Surgery For many patients, the prospect of surgery can be daunting due to the associated risks, downtime, and long recovery periods
No one has a magic eight ball, but management teams and investors are thinking long and hard about the impacts these drugs could have worldwide
Dam, Tine Vrist, et al
Too much variation in either direction creates problems: Doses too far apart (9+ days): blood levels drop below the therapeutic threshold, reducing appetite suppression and glucose control Doses too close together (5 days or less): blood levels climb higher than intended, increasing nausea, vomiting, and other GI side effects The question "can I take it a day early" is really asking: how much timing flexibility exists before I create one of those two problems
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