Specifically, nerve damage caused by vitamin B12 most often affects the extremities (hands and feet)
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Although we expected the largest microbiome differences to occur in the lean control group relative to the obese control group, we found that the diet-switched groups exhibited a greater number of differences from the control groups than the control groups did from one another
[6] After parenteral delivery, cyanocobalamin binds transcobalamin II, permitting receptor mediated endocytosis into virtually all nucleated cells
Co-enzyme B12 also interacts with the enzyme methionine synthase (5-methyltetrahydrofolate-homocysteine methyltransferase), required for the conversion of homocysteine to methionine, which is essential for folic acid metabolism and the formation of thymine, which is a component of DNA