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GLP-1 is broken down within 1 to 2 minutes of release in the body by the bodys enzymatic system, because it breaks down so quickly, native GLP-1 is not therapeutically useful as a drug
Patients should never self-combine prescription medications without clinician oversight
Most side effects are mild and go away over time
While frank hyperglycemia is uncommon, those with underlying insulin resistance or diabetes should be monitored for any change in glucose control
![Structures of (a) GLP-1, (b) GIP and (c) tirzepatide [19, 88, 90]](https://www.researchgate.net/publication/370926483/figure/fig4/AS:11431281185432337@1693619320519/Structures-of-a-GLP-1-b-GIP-and-c-tirzepatide-19-88-90-Amino-acids-are.png)
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