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Glucose phosphate isomerase (GPI), triosephosphate isomerase (TPI), and pyrimidine 5-nucleotidase (P5N) deficiency are included among the relatively rare causes of hereditary nonspherocytic hemolytic anemia

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USA 115 , E4061E4070 (2018)

Others have gone on to attribute symptoms of headache, asthma, hives, runny nose, muscle twitching and chest pain to MSG ingestion. However, well-controlled scientific studies have failed to produce consistent evidence that MSG causes these symptoms in the general population or even in people who self-identify as MSG-sensitive. A 2016 paper reviewed the connection between MSG and headache